Endocrine Abstracts

Introduction: Renal cell carcinoma (RCC) is the most common type of malignant renal tumors in adults. It is often difficult to detect it precociously since early-stage renal tumors are usually asymptomatic and non-palpable. We report a case of RCC revealed by acute adrenal insufficiency (AAI).Case report: Mr. A.B, 46 years old, 30 pack-year smoker, with a medical history of gout treated with Allopurinol, was admitted to our department for acute adrenal i...

Introduction: The COVID-19 pandemic had a significant emotional and psychological impact on populations worldwide, especially vulnerable people with chronic diseases such as diabetics. The objective of our study was to assess the quality of life and psychological distress of diabetic patients and to study patients’ attitudes towards managing their diabetes.Methods: We conducted a cross sectional descriptive study involving 60 diabetic patients follo...

Introduction: Adrenal adenomas development has been partially explained by aberrant adrenal expression of some hormone receptors. Klinefelter’s syndrome is a common cause of hypergonadotropic hypogonadism, which is characterized by increased serum LH level. In this case, we report a patient with Klinefelter syndrome, who was later diagnosed with a non secreting adrenal adenoma.Case presentation: We report the case of a 57 years old patient, diagnose...

Introduction: Gelastic seizures have been typically described with hypothalamic hamartomas and precocious puberty. Invasive EEG recordings have shown that gelastic seizures originated from the hypothalamic hamartomas, however recent findings have shown that they might also arise from other central lesions, like tumors, malformations of cortical development, postinfectious foci and other hypotalamic or pituitary abnormalities. In this case, we describe a patient with gelastic s...

Introduction: Pituitary stalk interruption syndrome is a rare disorder characterized by a specific tirade: an absent or hypoplastic anterior pituitary gland, thin or absent infundibulum, and ectopic posterior pituitary location. This syndrome has been described in association with other somatic abnormalities and recently a polygenic etiology has been suggested. Herein, we report a case of type 1 diabetic patient, explored for short stature, revealing a pituitary stalk interrup...

Introduction: Growth hormone deficiency (GHD) is a rare cause of delay of growth. However, it is primordial to screen for it since its presence leads to a specific treatment which improves statural prognosis. GHD should be confirmed through stimulation tests such as Insulin Tolerance test (ITT) or Clonidine Stimulation Test (CST). The objective of our study was to compare these two diagnostic tools.Methods: We conducted a retrospective study in the endoc...

Introduction: The glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency in humans. In red blood cells, the pentose phosphate pathway is the only source of nicotinamide adenine dinucleotide (NADPH), and defense mechanisms against oxidative damage are highly dependent on G6PD activity. The occurrence of acute haemolysis in patient with G6PD deficiency and diabetes has been reported and ascribed to various mechanisms. Her we report a case of pat...

Introduction: Obesity exposes to multiple complications, including cardiovascular and metabolic ones. It can also cause respiratory problems, which are still insufficiently researched. The objective of this study was to detect respiratory abnormalities in a group of obese people followed in an obesity unit.Methods: This was a descriptive and analytical cross-sectional study of 100 obese patients consulting at the human obesity research unit of the Nation...

Aim of the studyTo identify the factors predicting insulin need in women with Gestational Diabetes Mellitus (GDM).MethodsIt was a retrospective study conducted in the National Institute of Nutrition between January 2018 and January 2019. Pregnant women referred for the management of GDM were included (n = 1000).GDM was defined according to the World Health Organisation as a glucose intolerance of var...

Background: The management of diabetic foot starts with prevention, mainly based on the early detection of peripheral neuropathy and peripheral arterial disease, called podiatric risk assessment. This risk must be evaluated in all type 2 diabetics since the discovery. The aim of this study was the assessment of diabetic foot ulcer risk according to International Working Group on the Diabetic Foot (IWGDF) and the identification of risk factors for developing foot lesions.<p...